Endocrine Abstracts

Context: Recent studies showed association between hyperaldosteronism and low bone density among patients with primary aldosteronism (PA) due to secondary hyperparathyroidism.Objective: To assess bone turnover markers and bone mineral density (BMD) of PA patients compared to essential hypertension.Design: This was an open label, prospective, case-controlled study, conducted over 12 months.Setting: Eighteen co...

IntroductionGlucagon-like peptide-1 (GLP-1) plays an important role in the pathophysiology of type 2 diabetes mellitus (T2DM). However, results from previous studies on the GLP-1 secretory responses in individuals with different glucose tolerance states remain controversial. This may be contributed by the heterogeneous characteristics of the patients recruited.AimTo examine whether GLP-1 secretion is affected...

IntroductionGlucagon-like peptide-1 (GLP-1) plays an important role in the pathophysiology of type 2 diabetes mellitus (T2DM). Results from some studies on post-OGTT GLP-1 responses involving East Asians with abnormal glucose tolerance states tend to differ from the West. This may be attributed to the different diabetic phenotypes found in East Asians.AimTo examine post-OGTT GLP-1 responses in subjects with n...

Introduction: Acute myocardial infarction (AMI) is a stressful condition in which it stimulates the hypothalamus-pituitary-adrenal axis leading to mark increase in the production of cortisol. Adrenal insufficiency (AI) has been shown to be associated with morbidity and mortality in acute coronary syndrome patients. To date, none study has been performed to determine prevalence of AI among patient with AMI.Objectives: The aim of this study is to determine...

Introduction: Acute ischaemic stroke is a stressful condition in which there is marked increase in the production of cortisol. In the past adrenal insufficiency in critically ill patients had been shown to be associated with significant morbidity and mortality. To date there is no study performed to determine its prevalence among patients with acute ischaemic stroke.Objectives: The aim of this study is to determine the prevalence of relative adrenal insu...

Introduction: Refined carbohydrates, which constitute the staple diet in most cultures may exaggerate postprandial responses in term of insulin, free fatty acid and vascular function. These changes may contribute the onset of metabolic syndrome and diabetes among those at high risk of developing these diseases.Objective: To determine the postprandial insulin, free fatty acids levels and endothelial function responses in healthy subjects to two different ...

BackgroundThe burden of disease in thyroid dysfunction (TD) is modifiable. Social domain of quality-of-life is a vital aspect of the biopsychosocial approach to management. Treatment decisions are increasingly guided by quality-of-life issues, creating a need to monitor the quality-of-life within clinical practice. Thyroid-specific patients reported outcomes scale/tool (ThyPro) was developed and used predominantly in populations in developed countries. W...